(In text citation, references)
P. R. is a 24-year-old male who presents to urgent care with complaints of rectal bleeding and weakness. Five days ago he noticed bright red blood in his stools.  His daily bowel movements have increased to five or six with significant diarrhea.  He states that urges to move his bowels have rapid onset but there is not incontinence.  He has be week for approximately 2 ½ days.  He has not traveled outside of the city, been hospitalized or received antibiotics recently.  
He has a strong positive family history of autoimmune disease on the maternal side.  His mother has SLE.  He maternal grandmother had Graves disease and his aunt has myasthenia gravis. 
A protosigmoidoscopy revealed significant pseudopolyps and inflammation and ulceration were seen in the rectum and the sigmoid colon.

What is the differential diagnosis for this case?
What is the most likely diagnosis for this patient? 
Compare and contrast P.R.’s condition with another Inflammatory Bowel Disease.

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